Alessandro Maccione

Other Publications

Papers

• "Beam induced deposition of 3D electrodes to improve coupling to cells" L Martiradonna, L Quarta, L Sileo, A Schertel, A Maccione, A Simi, A Dante, A Scarpellini, L Berdondini and M De Vittorio – Microelectronic Engineering, ISSN 0167-9317 (2012) doi:10.1016/j.mee.2012.03.027
• “Emergent functional properties of neuronal networks with controlled topology“ E Marconi, T Nieus, A Maccione, P Valente, A Simi, M Messa, S Dante, P Baldelli, L Berdondini and F Benfenati – PloS ONE  7(4):  e34648. (2012) doi:10.1371/journal.pone.0034648
• “Multiscale functional connectivity estimation on low density neuronal cultures recorded by high density CMOS Micro Electrode Arrays“ A Maccione, M Garofalo, T Nieus, M Tedesco, L Berdondini and S Martinoia – Journal of Neuroscience Methods, Vol 207, Issue 2 (2012) doi:10.1016/j.jneumeth.2012.04.002
• “Combined optical tweezers and laser dissector for controlled ablation of functional connections in neural networks“  F Difato, M Dal Maschio, E Marconi, G Ronzitti, A Maccione, T Fellin, L Berdondini, E Chieregatti, F Benfenati and A Blau – Journal of Biomedical Optics 16(5), 051306 (2011) doi: 10.1117/1.3560268
• "Tracking burst patterns in hippocampal cultures with high-density CMOS-MEAs" M Gandolfo, A Maccione, M Tedesco, S Martinoia and L Berdondini – Journal of Neural Engineering, 7 - 056001 (2010) doi:10.1088/1741-2560/7/5/056001
• “Investigating neuronal activity by SPYCODE multichannel data analyzer“ L L Bologna, V Pasquale, M Garofalo, M Gandolfo, P L Baljon, A Maccione, S Martinoia and M Chiappalone – Neural Networks, 23 685-697 (2010)
• “Experimental investigation on spontaneously active hippocampal cultures recorded by means of high-density MEAs: analysis of the spatial resolution effects“ A Maccione, M Gandolfo, M Tedesco, T Nieus, K Imfeld, S Martinoia and L Berdondini – Frontiers in Neuroengineering (2010) doi: 10.3389/fneng.2010.00004
• “Reliability of kinematic parameters during unilateral upper limb reaching tasks using a portable motion tracking system“ M B Warner , A Novellino , M Stokes , S Astill and A Maccione – Journal of Medical Engineering & Technology, Vol 3, No 3, Pages 200-208 (2010)
• “Active pixel sensor array for high spatio-temporal resolution electrophysiological recordings from single cell to large scale neuronal networks“ L Berdondini, K Imfeld, A Maccione, M Tedesco, S Neukom, M Koudelka-Hep and S Martinoia – Lab on a Chip, 9, 2644 - 2651, (2009) doi: 10.1039/b907394a
• “Extracellular recordings from high density microelectrode arrays coupled to dissociated cortical neuronal cultures” L Berdondini, P Massobrio, M Chiappalone, M Tedesco, K Imfeld, A Maccione, M Gandolfo, M Koudelka-Hep and S Martinoia – Journal of Neuroscience Methods, vol. 177, pp. 386–396 (2009) doi10.1016/j.jneumeth.2008.10.032
• “Real-time signal processing for high-density MEA systems” K Imfeld, A Maccione, M Gandolfo, S Martinoia, M Koudelka-Hep and L Berdondini – International Journal of Adaptive Control and Signal Processing (2009)
• “Neural Signal Manager: a collection of classical and innovative tools for multichannel spike train analysis” A Novellino, M Chiappalone, A Maccione and S Martinoia – International Journal of Adaptive Control and Signal Processing (2009)
• “A novel algorithm for precise identification of spikes in extracellularly recorded neuronal signals” A Maccione, M Gandolfo, P Massobrio, A Novellino, S Martinoia and M Chiappalone – Journal of Neuroscience Methods (2009) doi:10.1016/j.jneumeth.2008.09.026
• “Large-scale, High-Resolution Data Acquisition System for Extracellular Recording of Electrophysiological Activity“ K Imfeld, S Neukom, A Maccione, Y Bornat, S Martinoia, P-A Farine, M Koudelka-Hep and L Berdondini – IEEE Transactions on Biomedical Engineering, vol. 55, no. 8 (2008) doi:10.1109/TBME.2008.919139

Book Chapters

• “Process Biomimetics In Tissue Engineering: Engineering The In Vitro Tissue Development Through Systems Biology And Networks Science” P Lenas, F P Luyten, V Saravia, J-L Toca-Herrera, L Ikonomou, E Nicodemo-Lena, A Ito, H Honda, A Dinnyes, J Mayer, I Arzimanoglou, F M Gordillo, A Maccione, A Guzmán-Aránguez and J Pintor, “Biomimetics in Biophysics: Model systems, experimental techniques and computation”, Ed. Jose L. Toca-Herrera, Publisher, Research Signpost, Kerala, India (2008)

Proceedings

• ”Structured neuronal networks investigated by high-resolution MEAs“ A Simi, A Bosca, A Maccione, T Nieus, F Brandi, S Dante and L Berdondini – FENS Forum 14-18 July Barcellona (2012)
• ”A joint structural and functional analysis of in-vitro neuronal networks“ S Ullo, A Del Bue, A Maccione, L Berdondini and V Murino – International Conference on Image Processing 30 Sept – 3 Oct Orlando Florida (2012)
• ”Coupling neuronal cultures grown on flexible laser-etched porous membranes with CMOS-MEA” E Marconi, A Maccione, A Simi, A Bosca, F Brandi, F Benfenati, S Dante and L Berdondini – The 6th International Conference on Microtechnologies in Medicine and Biology (MMB 2011), May 4-6, Luzern, Switzerland (invited, conference local co-organizer) (2011)
• “What can MaxEnt reveal about high-density recordings and what can high-density recordings reveal about MaxEnt?” D Panas, A Maccione, L Berdondini and  MH Hennig – 20th Annual Computational Neuroscience Meeting (CNS), July 23-28, held at the Royal Institute of Technology in Stockholm, Sweden (2011)
• “Analysis of simultaneous multielectrode recordings with 4,096 channels: changing dynamics of spontaneous activity in the developing retina” MH Hennig, A Maccione, M Gandolfo, M Down, SJ Eglen, L Berdondini and E Sernagor – 20th Annual Computational Neuroscience Meeting (CNS), July 23-28, held at the Royal Institute of Technology in Stockholm, Sweden (2011)
• “Engineering biological networks to investigate the computations performed by real neural networks” T Nieus, E Marconi, A Maccione, S Panzeri and L Berdondini – 20th Annual Computational Neuroscience Meeting (CNS), July 23-28, held at the Royal Institute of Technology in Stockholm, Sweden(2011)
• “Multisite recording techniques in network electrophysiology – Part 1: Conventional MEAs and high-resolution MEAs” L Berdondini, T Nieus and A Maccione – SIF2011 School of Physiology - New technologies for the study of the central nervous system, 5th of April,  Genova, Italy (2011)
• “Investigating 2D/3D patterned networks coupled with high-resolution MEAs for functional studies” A Simi, E Marconi, A Maccione, T Nieus, A Bosca, F Brandi, F Benfenati, S Dante and L Berdondini – 8th IBRO World Congress of Neuroscience - July 14-18,  Florence, Italy (2011)
• “Validation of a high-density microelectrode array for acute brain slice recordings” E Ferrea, L Medrihan, A Maccione, P Baldelli, D Ghezzi, F Benfenati and L Berdondini – 8th IBRO World Congress of Neuroscience - July 14-18, Florence, Italy (2011)
• “Imaging Neurodynamics with High-Resolution Electrode Arrays” L Berdondini and A Maccione – TPB International Symposium, July 16-22, St-Petersburg- N. Novgorood, Russia (invited) (2011)
• “Investigating 2D/3D patterned networks coupled with high-resolution MEAs for functional studies” A Simi, E Marconi, A Maccione, T Nieus, A Bosca, F Brandi, F Benfenati, S Dante and L Berdondini – 62° Congresso Nazionale della Società Italiana di Fisiologia, Sept. 25-27, Sorrento, Italy (invited) (2011)
• “Beam induced deposition of 3D electrodes to improve coupling to cells” L Martiradonna, L Quarta, L Sileo, A Schertel, A Maccione, A Simi, L Berdondini and M De Vittorio – 37th International Conference on Micro and Nano Engineering (MNE2011), Sept. 19 – 23, Berlin, Germany (2011)
• “Dissecting the orchestrated electrical activity in neuronal networks: a multimodal approach combining high density MEAs with fluorescence imaging” A Maccione, S Ullo, A Simi, A Del Bue, E Petrini, A Barberis, V Murino and L Berdondini - Proc. SFN Washignton, USA, Nov. 12-16, Washington DC, USA (2011)
• “Validation of a high-density microelectrode array for acute brain slice recordings” E Ferrea, L Medrihan, A Maccione, P Baldelli, D Ghezzi, F Benfenati, L Berdondini – Proc. SFN Washignton, USA, Nov. 12-16, Washington DC, USA (2011)
• “Loss of tonic inhibition underlies cortico-hippocampal network hyperexcitability in the Synapsin II KO mice” L Medrihan, E Ferrea, A Maccione, L Berdondini, P Baldelli, F Benfenati – Proc. SFN Washignton, USA, Nov. 12-16Washington DC, USA (2011)
• “High resolution spatiotemporal analysis of mouse retinal waves during postnatal development” E Sernagor, MH Hennig, A Maccione, M Gandolfo, M Down, J van Coppenhagen, S Eglen and L Berdondini – Proc. SFN Washignton, USA, Nov. 12-16 Washington DC, USA (2011)
• “Beyond correlations in MEA recordings – how far can we go?” D Panas, A Maccione, L Berdondini and MH Hennig – Proc. SFN Washignton, USA, Nov. 12-16 Washington DC, USA (2011)
• "Improved spatial-temporal analysis capabilities by high-resolution MEAs: in-vitro experimental investigations" A Maccione, M Gandolfo, S Martinoia and L Berdondini – SFN San Diego (2010)
• "Changing dynamics of spontaneous waves during retinal development: a novel panretinal perspective achieved with the Active Pixel Sensor (APS) 4,096 electrodes array" E Sernagor, A Maccione, M Hennig, M Gandolfo, S Eglens and L Berdondini – SFN San Diego (2010)
• "Recording retinal waves with a 4,096 electrodes array: novel analytical and data sharing tools" E Sernagor, A Maccione, M Gandolfo, S Eglen, M Hennig and L Berdondini – INCF Kobe (2010)
• "Functional and morphological comparison of patterned and random low density cultures of neurons grown on microelectrode arrays (MEAs)" E Marconi, M Messa, P Baldelli, S Casagrande, S Dante, A Maccione, L Berdondini and F Benfenati –  MEA Meeting Reutlingen (2010)
• "Changing dynamics of spontaneous waves during retinal development: a novel panretinal perspective achieved with the Active Pixel Sensor (APS) 4,096 electrodes array" E Sernagor, A Maccione, M Hennig, M Gandolfo, SJ Eglen and L Berdondini –  MEA Meeting Reutlingen ORAL (2010)
• "Investigation of pharmacologically-induced epileptic spatial-temporal patterns on cortico-hippocampal slices by means of high-density microelectrode Arrays" E Ferrea, A Maccione, P Baldelli, F Benfenati and L Berdondini -  MEA Meeting Reutlingen (2010)
• "Investigating neuronal networks dynamics in hippo-campal cultures by means of high-density CMOS-MEAs" M Gandolfo, A Maccione, M Tedesco, T Nieus, K Imfeld, S Martinoia and L Berdondini – MEA Meeting Reutlingen, ORAL (2010)
• "Functional Connectivity Maps In Hippocampal Cultures Coupled To High Resolutions MEAs Underlie Structural Connectivity" A Maccione, M Garofalo, T Nieus, M Tedesco, E Commisso, S Martinoia and L Berdondini – MEA Meeting Reutlingen (2010)
• "Functional and morphological comparison of patterned and random low density cultures of neurons grown on microelectrode arrays (MEAs)" E Marconi, S Dante, P Baldelli, M Casagrande, M Messa, A Maccione, L Berdondini and F Benfenati – FENS Amsterdam (2010)
• "Investigation of the spatial-temporal propagation pattern of epileptic events on cortico-hippocampal slices by means of high-density micro electrode arrays" E Ferrea, A Maccione, P Baldelli, F Benfenati and L Berdondini –FENS Amsterdam (2010)
• "Increased spatial-temporal analysis capabilities by high-resolution MEAs: in-vitro experimental investigations" A Maccione, M Gandolfo, S Martinoia and L Berdondini – Frontiers in Neuroengineering Monte Verità - Ascona, September 5th - 9th (2010)
• “Active Pixel Sensor Micro Electrode Arrays (APS-MEA): analysis of the network dynamics from large scale hippocampal neuronal populations recorded at high spatio-temporal resolution” M Gandolfo, K Imfeld, M Tedesco, A Maccione, L Berdondini and S Martinoia – SFN Chicago (2009)
• “Active Pixel Sensor Micro Electrode Arrays (APS-MEA): perspectives and challenges using a high resolution neuroelectronic interface for functional electrophysiological imaging of in-vitro neuronal networks and acute brain slice” A Maccione, M Gandolfo, K Imfeld, M Tedesco, S Martinoia and L Berdondini – SFN Chicago (2009)
• “Functional connectivity of cortical networks in vitro and neuronal avalanches: linking network topology to cascading dynamics“ S Martinoia, M Garofalo, V Pasquale, P Massobrio, T Nieus, A Maccione, L Berdondini and F Benfenati – SFN Chicago (2009)
• “Imaging extracellular neuronal signaling on high resolution micro electrode arrays“ A Maccione, K Imfeld, M Gandolfo, M Tedesco, M Koudelka-Hep, F Benfenati, S Martinoia and L Berdondini – 4th International IEEE EMBS Antalya Turkey (2009)
• “Enabling high-resolution extracellular recordings from in-vitro neuronal networks“ A Maccione, K Imfeld, M Gandolfo, M Tedesco, S Martinoia, F Benfenati and L Berdondini – Neuroelectronic Hybrids System School, Jerusalem, 15-19 March, 2009
• “A 4096 high resolution microelectrodes array platform for exploring neuronal circuitries” L Berdondini, A Maccione, M Gandolfo, K Imfeld, F Benfenati and S Martinoia – Invited Talk at Technion, Haifa, Israel, 14 Jannuary (2009)
• “Exploring Neuronal Circuitries: a 4096 High Resolution Microelectrodes Array Platform” A Maccione, K Imfeld, S Martinoia, M Koudelka-Hep and L Berdondini –  Bioengineering 2008, 18-19 September, London (UK) ORAL (2008)
• “APS-MEA Platform for High Spatial and Temporal Resolution Recordings of In-Vitro Neuronal Networks Activity” L Berdondini, K Imfeld, M Gandolfo, S Neukom, M Tedesco, A Maccione, S Martinoia and M Koudelka-Hep – Mea Meeting 08, 8-11 July, Reutlingen (Germany) (2008)
• “Hardware-based real-time signal processing for high-density MEA systems“ K Imfeld, L Berdondini, A Maccione, S Martinoia, PA Farine and M Koudelka-Hep – Mea Meeting 08, 8-11 July, Reutlingen (Germany) (2008)
• “New Software Analysis Tool for Managing High Density MEA Systems” A Maccione, M Gandolfo, M Mulas, L Berdondini, K Imfeld, S Martinoia and M Koudelka-Hep – Mea Meeting 08, 8-11 July, Reutlingen (Germany) (2008)
• “ARTEMIS Project - In Vitro 3D Neural Tissue System For Replacement Transgenic Animals With Memory/Learning Deficiencies” A Novellino, A Maccione, M Mulas, A Moreno, E Nicodemou-Lena, C Pizarro,  L Lopez, A Lanzara, S Cobena, P Lenas – Mea Meeting 08, 8-11 July, Reutlingen (Germany) (2008)
• “Cultured neuronal networks coupled to innovative high density micro electrode arrays” A Maccione, M Gandolfo, K Imfeld, L Berdondini, S Martinoia – GNB - First Bioengineering National Congress, 3-5 July, Pisa (Italy) (2008)
• “An Innovative 3D In Vitro Model for Eletrophysiological Screening in Neurotoxicology and Neuropharmacology” A Novellino, A Maccione, A Moreno, E Nicodemou-Lena, C Pizarro, L Lopez, A Lanzara, S Cobena and P Lenas – GNB - First Bioengineering National Congress, 3-5 July, Pisa (Italy) (2008)
• “Reliability of Speed Characteristics During Reaching Tasks Using the Motor Task Manager in Healthy Males” A Novellino, M Warner, S Astill, A Maccione and M Stokes – GNB - First Bioengineering National Congress, 3-5 July, Pisa (Italy) (2008)
• “High-Resolution MEA Platform for In-Vitro Electrogenic Cell Networks Imaging” K Imfeld, A Garenne, N Simon, A Maccione, S Martinoia, M Koudelka, L Berdondini- 29th IEEE EMBS Annual International Conference (2007)
• “Activity Modulation Elicited by Electrical Stimulation in Networks of Dissociated Cortical Neurons” P Massobrio, PL Baljon, A Maccione, M Chiappalone and S Martinoia – 29th IEEE EMBS Annual International Conference (2007)
• “Motor Task Manager an Innovative System for Diagnosis and Rehabilitation of the Upper Limbs”  A Maccione and A Novellino – Medical Instrumentation NY-Day (2007)
• “A novel spike detection algorithm for real-time applications” A Novellino, A Maccione, M Gandolfo, M Chiappalone, P Massobrio and S Martinoia – 5th Int. Meeting on Substrate-Integrated Microelectrodes, (2006)
• “Sistema integrato per la diagnosi e la valutazione riabilitativa dell’arto superiore” E Pittaluga, A Novellino and A Maccione – eTT s.r.l., Università degli studi di Genova – Biosys (2005)
• “Effects of Cognitive Workload and Alcohol on Arm Movements” E Pittaluga, A Maccione and A Novellino – DiBE, University of Genoa, Italy; R&D Lab, eTT s.r.l., Genoa, Italy – SIAMOC ORAL (2005)