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People ■ Esther Torrente De Haro
Esther Torrente De Haro's foto

Esther Torrente De Haro

Post Doc

iit / Drug Discovery and Development


Phone +39 010 71781845

Bio

Esther Torrente was educated at the University Autónoma de Madrid (Spain) where she graduated in Chemistry  in 2003. 
She received her PhD in Organic Chemistry from the same Institution in 2010 under the supervision of Prof Jose Luis Garcia Ruano, working on “Asymmetric Synthesis of Quaternary Stereogenics carbons Mediated by a Remote Sulfinyl Group”. 


As a part of her PhD program, Esther spent 4 months in 2006 as visiting scientist in the laboratory of Prof. Saverio Florio, Department of Pharmacy and Chemistry, Università degli Studi di Bari (Italy), working on “Synthesis and Reactivity of 2-p-Tolylsulfinylphenyloxiranes”. And more later in 2010 she spent 3 months in the laboratory of  Prof. Alessandro Degl’Innocenti, Department of Pharmacy, Università degli Studi di Firenze (Italy) working on “Synthesis of Enantiomerically pure 1,2-disubstituted 2-Selenoamines”.

In 2011, Dr. Torrente joined the group of Prof Prof. Stephen Connon, Department of Chemistry, Trinity College of Dublin (Ireland)  as Post-doctoral Fellow and her research project focused on the field organocatalyst and more concretly on synthesis and design of new organocatalyst

Dr. Torrente joined the Italian Institute of Technology (IIT) in Febrary 2012 as Junior Post-doctoral Fellow in the Drug Discovery and Development Department (D3).

Esther Torrente was educated at the University Autónoma de Madrid (Spain) where she graduated in Chemistry  in 2003. 
She received her PhD in Organic Chemistry from the same Institution in 2010 under the supervision of Prof Jose Luis Garcia Ruano, working on “Asymmetric Synthesis of Quaternary Stereogenics carbons Mediated by a Remote Sulfinyl Group”. 


As a part of her PhD program, Esther spent 4 months in 2006 as visiting scientist in the laboratory of Prof. Saverio Florio, Department of ...

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Selected Publications

Publications

  • "Stereoselective Michael additions of lithiated ortho-sulfinylbenzyl carbanions derived from α-amino nitriles"  García Ruano, J. L.;  Martín-Castro, A. M.; Moreno L.; Tato F.; Torrente E. J. Sulf. Chem. 2013, 

  • "Use of Lithiated Chiral o‑Sulfinylbenzyl Carbanions for the One-Pot Building of Linear Fragments Containing up to Four Connected Stereocenters" García Ruano, J. L.; Torrente, E.; Martín-Castro, A. M. J. Org. Chem. 201378, 647.
  • "Asymmetric Intramolecular Pauson–Khand Reaction Mediated by a Remote Sulfenyl or Sulfinyl Group"; García Ruano, J. L.; Torrente, E.; Parra, A.; Alemán J.; Martín-Castro, A. M. J. Org. Chem. 201277, 6583.
  • ·A Catalytic Asymmetric Reaction using Anhydrides as Nucleophiles”; C.Cornaggia, C.; Manoni, F.; Torrente, E.; Tallon, S.; Connon, S. J. Org. Lett. 2012, 14, 1850.    
  • ·Synthesis of Enantiomerically Pure anti-1,2-Diaryl and syn-1,2-Alkylaryl vic-Selenoamines”; García Ruano, J. L.; Torrente, E.; Alonso, I.; Rodriguez,  M.; Martín-Castro, A. M.; Degl’Innocenti, A.; Frateschi, L.; Capperucci, A.J. Org. Chem. 2012, 77, 1974.
  • ·“Asymmetric Synthesis of Benzylic Quaternary Difunctionalized Carbons Mediated by a Remote Sulfinyl Group”; García Ruano, J. L.; Torrente, E.; Martín-Castro, A. M. J. Org. Chem.2011, 76, 3597.
  • ·“Diastereodivergent Synthesis of Benzylic Quaternary Centers Mediated by a Remote Sulfinyl Group. Spectroscopic Evidences of the Structure of the Carbanionic Intermediates”, García Ruano, J. L.; Martín-Castro, A.; Torrente, E.; M. Poveda, A.; Phosphorus, Sulphur, and Sylicon, and the Related Elements, 2011,186,1119.
  • ·” García Ruano, J. L.; Martín-Castro, A. M.; Torrente E.; Degl`Innocenti, A.; Capperucci, A.; Frateschi, L; Phosphorus, Sulphur, and Sylicon, and the Related Elements, 2011,186,1268.
  • ·“Stereodivergent Quaternization of 2-Alkyl-2-p-Tolylsulfinyl 2-Alkyl Acetonitriles. NMR evidences of Planar and Pyramidal Benzylcarbanions”; García Ruano, J. L.; Martín-Castro, A. M.; Tato, F.; Torrente, E.; Poveda, A. M. Chem. Eur. J. 2010, 16, 6317.
  • ·“Stereoselective Synthesis of 2,3-Epoxy Alcohols mediated by a Remote Sulfinyl Group”; García Ruano, J. L.; Martín-Castro, A. M.; Tato F.; Torrente, E.; Tocco, M. G., Florio, S.; Capriati, V. Tetrahedron, 2010, 66, 1581.
  • ·“Influence of an ortho-Sulfinyl Group on the Configurational Stability of α-Lithiated Aryloxiranes: Deuteration of Tolylsulfinyl Styrene Oxides”; Capriati, V.; Florio, S.; Luisi, R.; Salomone, A.; Tocco, M. G.; Martín-Castro, A. M.; García Ruano, J. L.; Torrente, E. Tetrahedron, 2009, 65, 383-388.
  • ·“Asymmetric 1,3-Dipolar Reactions of Cyclic Vinyl p-Tolyl Sulfilimines with Diazoalkanes”; García Ruano, J. R.; González-Gutiérrez, L.; Torrente, E.; Martín-Castro, A.M. Arkivoc2005, 146-158.
  • ·“Efficient Enantioselective Synthesis of Cyclopropanes from Sulfonylpyrazolines”; García Ruano J. L.; Martín-Castro, A. M.; Torrente, E. Phosphorus, Sulphur, and Sylicon, and the Related Elements, 2005, 180, 1445-1446.·
  • “Efficient Synthesis of Enantiomerically pure a-Alkyl Cyclopropanecarbonitrile Derivatives from Pyrazolines”;García Ruano, J. L.; S. Alonso de Diego, S. A.; Martín, M. R.; Torrente, E.; A. M. Martín Castro. Org. Lett. 2004, 6, 4945-4948.

Patents:

  • 'Enantioselective organic anhydride reactions"' C. Cornaggia, F. Manoni, S. Tallon, E. Torrente and S. J. Connon,European Patent application, EP12159320.6 (March 2012) and US13/800,490 (March 2013).

Publications

  • "Stereoselective Michael additions of lithiated ortho-sulfinylbenzyl carbanions derived from α-amino nitriles"  García Ruano, J. L.;  Martín-Castro, A. M.; Moreno L.; Tato F.; Torrente E. J. Sulf. Chem. 2013, 

  • "Use of Lithiated Chiral o‑Sulfinylbenzyl Carbanions for the One-Pot Building of Linear Fragments Containing up to Four Connected Stereocenters" García Ruano, J. L.; Torrente, E.; Martín-Castro, A. M. J. Org. Chem. 201378, 647.
  • "Asymmetric ...

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