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People ■ Nicolas Boutard
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Nicolas Boutard

Post Doc

iit / Drug Discovery and Development

Phone +39 010 71781281

Selected Publications

  • ·N. Boutard, F. Labéguère, Y. Vidal, J-P. Lavergne, J. Martinez, New C-Glycosylated a-Amino Acids Synthesis by Addition Reaction of an Amino Acid Organozinc Reagent on Carbohydrate Derived-Aldehydes, Synth. Comm., 2012, 42, pp 1461-1471.
  • ·N. Boutard, J. Dufour-Gallant, P. Deaudelin, W. D. Lubell, Pyrrolo[3,2-e][1,4]diazepin-2-one Synthesis: A Head-to-Head Comparison of Soluble versus Insoluble Supports J. Org. Chem., 2011, 76, pp 4533-4545.
  • ·N. Boutard, S. Turcotte, K. Beauregard, C. Quiniou, S. Chemtob, W. D. Lubell, Examination of the Active Secondary Structure of the Peptide APG-101.10, an Allosteric Modulator of the Interleukin-1 Receptor, by Positional Scanning Using b-Amino g-Lactams, J. Pept. Sci., 2011, 17, pp 288-296..
  • ·N. Boutard, J. Dufour-Gallant, W. D. Lubell, Pyrrolo[3,2-e][1,4]diazepin-2-one γ-Turn Mimic Synthesis on TAP Soluble Support, Proceedings of the 31st European Peptide Symposium, M. Lebl, M. Meldal, K. J. Jensen, T. Hoeg-Jensen (Eds), European Peptide Society, 2011, pp 268-269. (http://www.eurpepsoc.com)
  • ·W. Lubell, A. Jamieson, N. Boutard, L. Ronga, D. St-Cyr, S. Turcotte, W. Chen, Processes for Preparing Amino-Substituted Gamma-Lactams, International Patent WO2010105367 (A1), 2010.
  • ·S. Chemtob, C. Quiniou, W. D. Lubell, S. Turcotte, N. Boutard, L. Ronga, A. G. Jamieson, D. St-Cyr, W. Chen, Interleukin-1 Receptor Antagonists and Uses Thereof, International Patent WO2010106441 (A2), 2010.
  • ·N. Boutard, A. G. Jamieson, H. Ong, W. D. Lubell, Structure-Activity Analysis of the Growth Hormone Secretagogue GHRP-6 by a- and b-Amino g-Lactam Positional Scanning, Chem. Biol. Drug. Des., 2010, 75, pp 40-50.
  • ·N. Boutard, A.G. Jamieson, W.D. Lubell, Solid-Phase Synthesis and CD Spectroscopic Conformational Analysis of a- and b-Amino g-Lactam (Agl and Bgl) Analogs of the Growth Hormone-Releasing Peptide GHRP-6, In Breaking Away: Proceedings of the 21st American Peptide Symposium, M. Lebl (Ed.), American Peptide Society : San Diego, 2009, pp 78-79 (http://www.5z.com/21staps/Proc21stAPS_CD_v6.pdf)
  • ·G. Jamieson, N. Boutard, K. Beauregard, M. S. Bodas, H. Ong, C. Quiniou, S. Chemtob, W. D. Lubell, Positional Scanning for Peptide Secondary Structure by Systematic Solid-Phase Synthesis of Amino Lactam Peptides, J. Am. Chem. Soc., 2009, 131, pp 7917–7927.
  • ·G. Fridkin, N. Boutard, W. D. Lubell, b,b-Disubstituted C- and N-Vinylindoles from One-Step Condensations of Aldehydes and Indole Derivatives J. Org. Chem., 2009, 74, pp 5603-5606.
  • ·E. Minta, C. Boutonnet, N. Boutard, J. Martinez, V. Rolland, Easy Saponification by Metal Silanolates: Application in SPPS and in (S)-5-Hydroxynorvaline Preparation, Tetrahedron Lett., 2005, 46, pp 1795-1797.
  • ·N. Boutard, F. Labéguère, Y. Vidal, J-P. Lavergne, J. Martinez, New C-Glycosylated a-Amino Acids Synthesis by Addition Reaction of an Amino Acid Organozinc Reagent on Carbohydrate Derived-Aldehydes, Synth. Comm., 2012, 42, pp 1461-1471.
  • ·N. Boutard, J. Dufour-Gallant, P. Deaudelin, W. D. Lubell, Pyrrolo[3,2-e][1,4]diazepin-2-one Synthesis: A Head-to-Head Comparison of Soluble versus Insoluble Supports J. Org. Chem., 2011, 76, pp 4533-4545.
  • ·N. Boutard, S. Turcotte, K. Beauregard, C. Quiniou, ...

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