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Francesca Succol Write a Message

Junior Technician

Contacts

Via Morego,30
+39 010 71781 782

About

Francesca Succol graduated in Biology at the University of Padova in 2004 studying muscle protein interactions by using luminescence oxygen channeling immunoassay (LOCI) technique. After the degree in Biology she spent 6 months working in the Prof. G. Valle Lab in the Department of Biology, Padova where she went on to study protein-protein interaction in the muscle. In the 2004 she got the Italian Qualification Test for Biologist profession. In 2005 she moved to the Department of Pharmacology, University of Pennsylvania, Philadelphia, in Prof. D. Praticò Lab, as graduate student, where she studied from 3/2005 to 6/2007 the Role of 12/15 lipoxygenase in Alzheimer’s disease pathogenesis. From 7/2007 to 2/2008 she moved to the Department of Neuroscience, University of Pennsylvania School of Medicine in Prof. SJ Moss, where she studied the Molecular determinant and trafficking of g-aminobutyric acid (GABA) receptors on the neuronal surface. In 2008 she moved to the Italian Institute of Technology (IIT) as a Junior Technician, Supervisor of the Cell Culture Facility in the Department of Neuroscience and Brain Technology. From 1/2009 to 4/2012 she followed the PhD program in Technological and Biomedical Sciences, University of Genoa. During her PhD she investigated the Role of Intracellular Chloride concentration in the GABAA Receptor subunit composition, working in the Dott. A. Barberis Lab in IIT. She has strong experience in cellular and molecular biology, biochemical and electrophysiology techniques.

 

Selected Publications

- Francesca Succol, Domenico Pratico’. A role for 12/15 Lipoxygenase in the Amyloid b Precursor Protein metabolism J. Neurochem. 2007 Oct; 103(1):380-7.  

 

- Tija Jacob, Qin Wan, Mansi Vithlani, Richard Saliba, Francesca Succol, Menelas Pangalos, Stephen Moss. GABAA receptor membrane trafficking regulates spine maturity. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12500-5. Epub 2009 Jul 14. July.

 

- Tommaso Fellin, Michael M. Halassa, Miho Terunuma, Francesca Succol, Hajime Takano, Stephen J Moss and Philip G. Haydon. Endogenous non neuronal modulators of synaptic transmission control cortical slow oscillations in vivo. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):15037-42. Epub 2009 Aug 17.

 

 

- Petrini EM, Thierry Nieus, Ravasenga T, Succol F, Guazzi S, Benfenati F, Barberis A. Influence of monoliganded states of GABAA R on GABAergic responses. J Neurosci. 2011 Feb 2;31(5):1752-61.

 

- Succol F., Fiumelli H, Benfenati F, Cancedda L and Barberis A. Intracellular chloride concentration influences the GABAA receptor subunit composition. Nat Commun. 2012 Mar 13;3:738.


- Jacob TC, Michels G, Silayeva L, Haydon J, Succol F, Moss SJ. Benzodiazepine treatment induces subtype-specific changes in GABAA receptor trafficking and decreases synaptic inhibition. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18595-600.

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I numeri di IIT

L’Istituto Italiano di Tecnologia (IIT) è una fondazione di diritto privato - cfr. determinazione Corte dei Conti 23/2015 “IIT è una fondazione da inquadrare fra gli organismi di diritto pubblico con la scelta di un modello di organizzazione di diritto privato per rispondere all’esigenza di assicurare procedure più snelle nella selezione non solo nell’ambito nazionale dei collaboratori, scienziati e ricercatori ”.

IIT è sotto la vigilanza del Ministero dell'Istruzione, dell'Università e della Ricerca e del Ministero dell'Economia e delle Finanze ed è stato istituito con la Legge 326/2003. La Fondazione ha l'obiettivo di promuovere l'eccellenza nella ricerca di base e in quella applicata e di favorire lo sviluppo del sistema economico nazionale. La costruzione dei laboratori iniziata nel 2006 si è conclusa nel 2009.

Lo staff complessivo di IIT conta circa 1440 persone. L’area scientifica è rappresentata da circa l’85% del personale. Il 45% dei ricercatori proviene dall’estero: di questi, il 29% è costituito da stranieri provenienti da oltre 50 Paesi e il 16% da italiani rientrati. Oggi il personale scientifico è composto da circa 60 principal investigators, circa 110 ricercatori e tecnologi di staff, circa 350 post doc, circa 500 studenti di dottorato e borsisti, circa 130 tecnici. Oltre 330 posti su 1400 creati su fondi esterni. Età media 34 anni. 41% donne / 59 % uomini.

Nel 2015 IIT ha ricevuto finanziamenti pubblici per circa 96 milioni di euro (80% del budget), conseguendo fondi esterni per 22 milioni di euro (20% budget) provenienti da 18 progetti europei17 finanziamenti da istituzioni nazionali e internazionali, circa 60 progetti industriali

La produzione di IIT ad oggi vanta circa 6990 pubblicazioni, oltre 130 finanziamenti Europei e 11 ERC, più di 350 domande di brevetto attive, oltre 12 start up costituite e altrettante in fase di lancio. Dal 2009 l’attività scientifica è stata ulteriormente rafforzata con la creazione di dieci centri di ricerca nel territorio nazionale (a Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) e internazionale (MIT ed Harvard negli USA) che, unitamente al Laboratorio Centrale di Genova, sviluppano i programmi di ricerca del piano scientifico 2015-2017.

IIT: the numbers

Istituto Italiano di Tecnologia (IIT) is a public research institute that adopts the organizational model of a private law foundation. IIT is overseen by Ministero dell'Istruzione, dell'Università e della Ricerca and Ministero dell'Economia e delle Finanze (the Italian Ministries of Education, Economy and Finance).  The Institute was set up according to Italian law 326/2003 with the objective of promoting excellence in basic and applied research andfostering Italy’s economic development. Construction of the Laboratories started in 2006 and finished in 2009.

IIT has an overall staff of about 1,440 people. The scientific staff covers about 85% of the total. Out of 45% of researchers coming from abroad 29% are foreigners coming from more than 50 countries and 16% are returned Italians. The scientific staff currently consists of approximately 60 Principal Investigators110 researchers and technologists350 post-docs and 500 PhD students and grant holders and 130 technicians. External funding has allowed the creation of more than 330 positions . The average age is 34 and the gender balance proportion  is 41% female against 59% male.

In 2015 IIT received 96 million euros in public funding (accounting for 80% of its budget) and obtained 22 million euros in external funding (accounting for 20% of its budget). External funding comes from 18 European Projects, other 17 national and international competitive projects and approximately 60 industrial projects.

So far IIT accounts for: about 6990 publications, more than 130 European grants and 11 ERC grants, more than 350 patents or patent applications12 up start-ups and as many  which are about to be launched. The Institute’s scientific activity has been further strengthened since 2009 with the establishment of 11 research nodes throughout Italy (Torino, Milano, Trento, Parma, Roma, Pisa, Napoli, Lecce, Ferrara) and abroad (MIT and Harvard University, USA), which, along with the Genoa-based Central Lab, implement the research programs included in the 2015-2017 Strategic Plan.